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Lyophilized fibrin sealant designed to stop severe bleeding | |||||||||||||
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ClotBlockŪ is a second-generation lyophilized fibrin sealant shaped as a compressed sponge, patch or gauze in various sizes and shapes to adapt to every surgical need. It bypasses fibrinogen cleavage, producing a strong fibrin polymer. | |||||||||||||
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Indication |
Control of intraopertive bleeding. Can be used as an adjunct to hemostasis or as primary treatment; no stitches or sutures needed. ClotBlock provides a flexible choice where arterial hemostasis is critically important. | |||||||||||||
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Mode of Action |
ClotBlock's fibrin-ready technology stanches the flow of blood from a lesion by gently pressing it against the surface of the organ for a few seconds. Produced as a solid cake, a flexible gauze, a small ball or catheter-size cylinder, ClotBlock offers flexibility to the surgeon by conforming to the contour of the organ. | |||||||||||||
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Advantages |
ClotBlock is a plasmin-depleted, aprotinin-free fibrin
presenting no risk of autoimmune reaction, and minimal risk of anaphylactic or systemic reaction to human
blood products. ClotBlock fibrin products can be kept at room temperature. |
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Developed with the support of the Defense Advanced Research Project Agency (DARPA), The National Heart, Blood, and Lung Institute (NHLBI) of the National Institutes of Health (NIH); The US Army Medical Research and Materiel Command (USAMRMC); the Maryland Technology Development Corporation (TEDCO ), Johnson & Johnson, and the University of Maryland |
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